A subtle role for HIF1α

A Subtle Role for Cd2 in T Cell Antigen Recognition

A fter the demonstration almost 20 years ago that anti-bodies to CD2 are potent inhibitors of T cell function, this cell surface glycoprotein became one of the most intensively studied of all T cell antigens (1–3). The subsequent identification of LFA-3 (CD58) as a ligand for human CD2 led to the demonstration in cell culture experiments that the CD2–CD58 interaction dramatically enhanced T cel...

A New Wavelet Based Spatio-temporal Method for Magnification of Subtle Motions in Video

Video magnification is a computational procedure to reveal subtle variations during video frames that are invisible to the naked eye. A new spatio-temporal method which makes use of connectivity based mapping of the wavelet sub-bands is introduced here for exaggerating of small motions during video frames. In this method, firstly the wavelet transformed frames are mapped to connectivity space a...

Subtle Hepatocellular Carcinoma: A Persisting Role for Alpha-Fetoprotein Monitoring in High-Risk Patients with Cirrhosis

Hepatocellular carcinoma (HCC) is a common, aggressive malignancy that usually develops in a background of liver cirrhosis. Practice guidelines recommend screening of cirrhotic patients with ultrasound and more detailed imaging (computed tomography or magnetic resonance imaging) if abnormalities are detected. The utility of alpha-fetoprotein levels in HCC surveillance is controversial. Although...

Subtle Mimicry of HLA by HIV-1 GP120 – A Role for Anti HLA Antibod- ies?

Human immunodeficiency virus (HIV-1) infection causes progressive immune deficiency by the targeted depletion of CD4+ T cells. The mechanism by which HIV-1 achieves this is not completely understood, however chronic immune activation is understood to be an essential feature of progressive HIV-1 infection. Although the mechanism by which HIV-1 induces chronic immune activation is also unknown, a...

A Subtle Role for CD 2 in T Cell Antigen Recognition